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Hotels in Cape Girardeau    Below is only a selection of Cape Girardeau Hotels. Search them all with the search box on the right.    Low Rate Guarantee! Read more Low Rate Guarantee Drury Lodge Cape Girardeau - Cape Girardeau 104 South Vantage Street Cape Girardeau, MO 63703 Information Enjoy a visit to Cape Girardeau's most complete hotel and conference center featuring the Cedar Street Restaurant and Bar with the finest in Texas style food. Conference facil More Check Rates Drury Suites Cape Girardeau - Cape Girardeau 3303 Campster Drive Cape Girardeau, MO 63703 Information Come stay with us in Cape Girardeau. Conveniently located at the intersection of I-55 and Route K. The hotel is just a short drive from Southeast Missouri State University Tra More Check Rates Pear Tree Inn Cape Girardeau - Cape Girardeau 3248 William Street Cape Girardeau, MO 63701 Information Enjoy a visit to Cape Girardeau. Located in an easily accessible area at a major I-55 exit and within blocks of shopping health care facilities and Southeast Missouri State Un More Check Rates Super 8 Motel - Cape Girardeau - Cape Girardeau 2011 North Kings Highway Cape Girardeau, MO 63701 Information Free Wireless High Speed Internet in all rooms Free Superstart Breakfast Refrigerators in all rooms Outdoor Pool Jacuzzi Suites available Bus/RV/Truck Parking Guest Laun More Check Rates Victorian Inn And Suites - Cape Girardeau 3265 William St. Cape Girardeau, MO 63702 Information Free breakfast with over 25 items, indoor heated pool, large whirlpool, deli and bar, free high speed wireless internet in every room, recently renovated, located right off of More Check Rates Holiday Inn Express Hotel & Suites Cape Girardeau I-55 - Cape Girardeau 3253 William St. Cape Girardeau, MO 63701 Information Welcome to the Holiday Inn Express Hotel & Suites Cape Girardeau. This newly built Cape Girardeau hotel opened in June 2005. Conveniently located at Interstate 55 and William More Check Rates Hampton Inn Cape Girardeau, Mo. - Cape Girardeau 103 Cape West Parkway Cape Girardeau, MO 63701 Information More Check Rates

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