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Hotels in Clarksdale    Below is only a selection of Clarksdale Hotels. Search them all with the search box on the right.    Low Rate Guarantee! Read more Low Rate Guarantee Comfort Inn Clarksdale - Clarksdale 818 South State Street Clarksdale, MS 38614 Information More Check Rates Americas Best Value Inn and Suites - Clarksdale - Clarksdale 350 South State Street Clarksdale, MS 38614 Information Welcome to the Americas Best Value Inn and Suites of Clarksdale, Mississippi. We are conveniently located on South State Street via US-278/MS-161. Our hotel is less than 1 mil More Check Rates

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