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Hotels in Santee    Below is only a selection of Santee Hotels. Search them all with the search box on the right.    Low Rate Guarantee! Read more Low Rate Guarantee Best Western Santee - Santee I-95 Exit 98 Santee, SC 29142 Information Choose this charming Santee, South Carolina hotel located less than two miles from the Santee State Park, the National Wildlife Refuge and several local golf courses. Welcome More Check Rates Holiday Inn SANTEE - Santee 139 Bradford Blvd Santee, SC 29142 Information Welcome to Santee South Carolina ® Golfers Paradise! Surrounded by history and beauty, the Holiday Inn Hotel Santee, provides you with Southern charm in a contemporary faci More Check Rates Howard Johnson Express Inn Santee SC - Santee 9112 Old # 6 Highway Santee, SC 29142 Information * 2005 Inn of the Year Award Winner * President's Quality Excellence Award * Free High Speed Internet * Complimentary Deluxe Continental Breakfast * Seasonal Outdoor Pool More Check Rates Super 8 Motel - Santee - Santee I-95 Exit 98 - Hwy 6 East Santee, SC 29142 Information * Welcome to the Super 8 in Santee- located in the heart of South Carolina's best golfing * Midway between New York and Florida, we are the perfect stop along the way * Ou More Check Rates Quality Inn & Suites - Santee 8929 Bass Drive Santee, SC 29142 Information Hotel features Golf and Fishing packages year round (call hotel direct for details), Lake Marion 1/2 mile, Carolina Grill Restaurant and Ziggy's Lounge located off hotel lobby More Check Rates Hampton Inn SanteeI95 - Santee 9060 Old #6 Highway Santee, SC 29142 Information The Hampton Inn Santee-I-95 SC hotel in South Carolina is located at I-95 Exit 98 and is a state-of-the-art interior corridor hotel with two elevators. The hotel is in the hea More Check Rates

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